Genmab Announces Investigational Rinatabart Sesutecan

From GlobeNewswire: 2025-06-02 14:30:00

Genmab A/S announced that the drug rinatabart sesutecan (Rina-S®) led to a 50.0% confirmed objective response rate in patients with advanced endometrial cancer, with a median duration of response not reached after 7.7 months. The Phase 2 RAINFOL™-01 trial is ongoing, with a planned Phase 3 trial in the works. This data was presented at the 2025 ASCO Annual Meeting in Chicago, Illinois. The study showed promising results for patients with limited treatment options, with encouraging early signals in endometrial cancer. The drug represents an innovative approach in addressing an unmet need for patients with advanced endometrial cancer. The Food and Drug Administration has granted Fast Track designation to Rina-S for the treatment of patients with specific types of ovarian cancer. Rina-S is currently in late-stage development with ongoing trials, including a planned Phase 3 trial. Genmab, the company behind Rina-S, is focused on developing innovative antibody therapeutics to improve patient outcomes. The safety and efficacy of Rina-S are still being evaluated in clinical trials. For more information, visit clinicaltrials.gov. Other recent studies have shown promising results for treatments targeting HER2 mutations, platinum-resistant ovarian cancer, and recurrent cervical cancer. Global cancer statistics show the ongoing need for effective treatment options for various types of cancer. 1. The US economy added 943,000 jobs in July, surpassing expectations and bringing the unemployment rate down to 5.4%. This is a positive sign of recovery following the impact of the pandemic.

2. A new study shows that the effectiveness of the Pfizer-BioNTech COVID-19 vaccine declines slightly over time, but remains highly effective in preventing severe illness and hospitalization.

3. The Tokyo Olympics are underway, with Team USA already securing several medals in various events. Despite challenges posed by the pandemic, athletes are showcasing their talents on the world stage.

4. Scientists have discovered a new species of dinosaur in Chile, which lived over 66 million years ago. The dinosaur, named Arackar licanantay, provides valuable insights into the prehistoric world.

5. The United Nations warns of a looming humanitarian crisis in Afghanistan, with millions of people facing food insecurity and displacement due to conflict and drought. Urgent action is needed to prevent widespread suffering.



Read more at GlobeNewswire: Genmab Announces Investigational Rinatabart Sesutecan