INE, a top enterprise IT training provider, responds to Cisco’s urgent security advisory on critical vulnerabilities in Cisco ISE and ISE-PIC. These flaws, with a maximum CVSS score of 10, allow unauthenticated remote attackers to execute commands with root privileges on affected systems. The vulnerabilities pose a severe threat to network security.

The three vulnerabilities, CVE-2025-20281, CVE-2025-20282, and CVE-2025-20337, have each been rated 10.0 on the CVSS scale. They impact ISE and ISE-PIC releases 3.3 and 3.4, allowing for remote exploitation without authentication. Attackers could gain root-level access, execute commands, move laterally, access sensitive data, and modify security policies.

Security experts, including Brian McGahan from INE, warn that these vulnerabilities create a cybersecurity nightmare scenario. Exploiting ISE could result in complete network compromise, making comprehensive network security training essential. Immediate action is required, with critical patches available for affected versions.

Organizations must take immediate action, upgrading to the latest patches for ISE releases. Those running affected versions should prioritize patching to prevent exploitation. Enhanced monitoring and access control reviews are recommended to mitigate risks. INE stresses the importance of incident response preparedness and ongoing IT training for cybersecurity teams.

The vulnerabilities were responsibly disclosed by security researchers and have not been actively exploited in the wild. However, given the critical nature of these flaws, security experts anticipate they will become high-priority targets for threat actors. INE emphasizes the need for continuous education and specialized training in vulnerability management and incident response.

INE Security, a premier provider of online networking and cybersecurity training, offers advanced technical training to help IT professionals excel in their careers. With a focus on lowering barriers for entry into the IT field, INE is committed to delivering expert cybersecurity training and certification to individuals and Fortune 500 companies worldwide.

Read more at GlobeNewswire: INE Security Alert: Critical Cisco ISE Vulnerabilities