In early trading, Synopsys led the Nasdaq 100, up 3.0%, while Strategy was the worst performer, down 6.9%. Year to date, Synopsys has lost 11.2% and Strategy is down 43.1%. Shopify fell 3.7% and Old Dominion Freight Line rose 1.6% on the day. Market movements are significant for investors.

Read more at Nasdaq: Nasdaq 100 Movers: MSTR, SNPS