AB Science has obtained Japanese patent protection for masitinib in progressive forms of multiple sclerosis (MS) until 2041. This marks the first country to grant the MS patent, highlighting masitinib’s unique positioning due to its safety and efficacy profile. The patent ensures intellectual property protection for masitinib, with similar strategies pursued for other indications. Masitinib’s development is based on positive phase 2b/3 studies, showing significant reduction in disability progression and improved manual dexterity. The drug targets mast cells and microglia, addressing the strong medical need for progressive MS treatment in the absence of definitive options. In progressive multiple sclerosis, innate immune cells like macrophages, microglia, and mast cells are key players. Treatments for MS have primarily targeted the adaptive immune system, leaving a high medical need for progressive forms of the disease. BTK inhibitors like tolebrutinib, evobrutinib, and fenebrutinib have shown mixed results in trials, with safety concerns and lack of efficacy in different forms of MS. Remibrutinib is currently the only BTK inhibitor in phase 3 trials for relapsing-remitting MS. AB Science is a pharmaceutical company focusing on protein kinase inhibitors, with their lead compound masitinib being developed for various diseases.
Read more at 1. “Tech Giant Apple Announces Record-breaking Q3 Earnings” – Globe Newswire
Apple reported a revenue of $81.4 billion for the third quarter, up 36% from last year. The company’s net income also soared to $21.7 billion, marking a 93% increase. iPhone sales were a major contributor to the impressive results, with a 50% growth compared to the previous year.
2. “Tesla Unveils Plans for Gigafactory in India” – Globe Newswire
Tesla CEO Elon Musk confirmed the company’s intention to build a Gigafactory in India, as part of its expansion strategy in the region. The facility is expected to produce electric vehicles and batteries, creating job opportunities and boosting the local economy.
3. “Amazon Launches Sustainable Packaging Initiative” – Globe Newswire
E-commerce giant Amazon announced a new initiative to reduce waste and promote sustainability by introducing recyclable packaging for its products. The company aims to eliminate plastic packaging by 2023 and achieve net-zero carbon emissions by 2040. Amazon’s commitment to environmental responsibility has been praised by consumers and environmental advocates alike.: AB Science receives Japanese patent protection for the use