In early trading, Strategy leads the Nasdaq 100 index with a 3.0% gain, but has lost 42.3% year to date. Biogen is the worst performer, down 2.9% today, with an 11.5% gain for the year. Diamondback Energy is down 2.4%, while Constellation Energy is up 2.2% on the day.

Read more at Nasdaq: Nasdaq 100 Movers: BIIB, MSTR